Source material screening, selection, collection and tracing
Working Group 1 is responsible for source material screening, selection, collection, and tracing. Together with immunology and cord blood bank experts from a number of countries, the team shall establish minimum criteria for sample quality, data and traceability in order to develop a common understanding of the (HLA) cord blood sample selection procedure.
Objectives
- Development of a common understanding of the /HLA / CB sample selection procedure
- Coordination of information seeking tracing, collection and data curation of the selected samples
WG1 Leaders
![CG-_0000_Sergio Querol](https://haplo-ips.eu/wp-content/uploads/2023/08/CG-_0000_Sergio-Querol.jpg)
![CG-_0003_Meral Beksac](https://haplo-ips.eu/wp-content/uploads/2023/08/CG-_0003_Meral-Beksac.jpg)
Meral Beksac
Description of Work
T1.1
Review of initiatives and literature on generation on hiPSC generation from haplo-selected CB samples (coordination and communication opportunities to understand the diversity and commonalities of approaches in different centres/countries) and organize an immunology expert meeting for CB sample selection (involving experts in HLA and non-HLA rejection and tolerance mechanisms).
T1.2
Contact (email, online conferences) CB EU banks for sample availability.
T1.3
CB bank expert meeting to establish minimal HAPLO-iPS criteria for sample quality (identifying appropriate standards for starting materials), data and traceability.
Deliverables and milestones
D1.1
Report on the common understanding of the haplo-selected CB samples selection procedure (M6).
D1.2
Report on the coordination of information seeking tracing, collection and data curation of the selected samples. (M15) M1.1: Decision on which CB samples need to be used for hiPSC generation and assess their availability.